I think Alex will go back to blaming herself rather. Pity. Brian/Alex would make a sweet couple indeed, though I don't see it happening soon. Alex clearly doesn't have romantic feelings for Brian(yet) and Brian is still too much of a nervous schoolboy to make much of an impression (the comparison with William was subtle, but apt). Still, my predictions for the next chapter -

a) Bonnie is going to pull through, and keep her mouth shut about following Brian that night.
b) Alex will dump Payton/Payton will dump Alex after finding out about Brian.
c) Alex and Brian will continue to be friends, but Alex will withdraw even more into herself.
d) Dianna Grimm is finally going to make an appearance.

Please give us a long, long chapter next time :)

-Jesse